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产品说明:
Nipacide BIT 20
Chemical name:1,2-Benzisothiazolin-3-one
Description:
Nipacide BIT 20 is a glycol based solution; low toxicity biocide developed for the
complete in-can protection of water based products. Nipacide BIT 20 is effective against
a wide range of microorganisms including gram positive and gram negative bacteria,
yeast and fungi. Microorganisms grow at a rapid rate and without use of the correct
biocide, numbers can increase dramatically.
Example of the numbers of bacteria able to grow in products if left unpreserved
•Time = 0 mins 1
•Time = 40 mins 4
•Time = 3 hrs 1024
•Time = 5 hrs 16,384
•Time = 7 hrs 1,048,576
•Time = 10 hrs 107,000,000,000
Time = 24 hrs
236,000,000,000,000,000,000,000
In-Can degradation in paints, polymer and adhesives as a result of bacterial and fungal
contamination, can result in:
•Loss of viscosity
•Gassing
•Discoloration
•Bad odors
•Product splitting
•Loss of adhesion
•Production clean down and production down time
•Loss of profit
Applications:
Nipacide BIT 20 is recommended for preservation of a wide range of applications
including water based, casein, animal bone based and PVA adhesives. Polymer emulsions
including, SBR latex, Polyvinyl acetate and acrylic. Water based decorative paints, metal
working fluids, Calcium Carbonate and Kaolin mineral slurries and concrete add-mixtures.
Nipacide BIT 20 is effective against a wide range of spoilage organisms and effective
over a wide pH and temperature range. Nipacide BIT 20 should be the biocide of choice
for products with pH >8 and production temperatures of >40 C.
Use level:
Nipacide BIT2 0 should be evaluated in finished products at levels between 0.1% and
0.25%. Please note that Nipacide BIT 20 above 0.25% requires R43 (causes
sensitization by skin contact) hazard labeling.
Microbiological data:
Nipacide BIT 20 has a broad spectrum of activity which is demonstrated by the
following MIC data.
MIC Levels Organism MIC (ppm)
Bacteria
Pseudomonas aeruginosa 300
Pseudomonas putida 250
Proteus vulgaris 25
Escherichia coli 25
Staphylococcus aureus 25
Fungi
Aspergillus niger 200
Penicillium mineoluteum 150
Fusarium solani 100
Geotrichum candidum 500
Yeast
Candida albicans 100
STANDARD FIVE CHALLENGE TEST METHOD: Bacterial Challenge Test.
Samples Tested: Water based decorative coating
INOCULUM
The mixed Inoculum of bacteria used is as follows : -
Bacteria:
Pseudomonas vesicularis Providentia rettgeri
Alcaligenes faecalis Flavobacterium odoratus
Enterobacter aerogenes
Escherichia coli
STANDARD FIVE CHALLENGE TEST METHOD: Fungal Challenge Test.
Samples Tested: Water based decorative coating
INOCULUM
The mixed Inoculum of fungi and yeast used is as follows : -
Fungi:
Fusarium solani
Geotrichum candidum
Aspergillus terreus
Yeast
Rhodotorula rubra
Saccharomyces cerevisiae
Chemical compatibility:
Nipacide BIT 20 is compatible wi th most raw materials used in the manufacture of
industrial products. Nipacide BIT20 compatibility should always be checked and
evaluated before use.
Clariant Technical Service:
Clariant technical service is available to assist customers in the determination of the
optimum use level of biocide required to fully protect their product. A dedicated team of
microbiologists are on hand at all times to assist customers with technical enquiries
relating to product protection. Full microbiological efficacy testing is available.
Regulations and approvals:
FDA 21 CFR 175.105 Adhesives
FDA 21 CFR 176.170 Components of paperboard in contact with aqueous and fatty foods
FDA 21 CFR 176.180 Components of paper and paperboard in contact with dry food.
BfR XIV Plastic dispersions
BfR XXXVI Preservative for Paper and Board
Use biocides safely. Always read the label and product information before use
September 2009
All information is given in good faith but without warranty. Customers should ensure
that their use of the products comply with specific regulations in the relevant market
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